Mucinous Tubular and Spindle Cell Carcinoma of Kidney: A Case Report of a Rare Tumor

Authors

  • Antonius Galih Pranesdha Putra Rumah Sakit Umum Daerah Dr. Mohamad Soewandhie, Jawa Timur, Indonesia
  • Taufik Indrawan Rumah Sakit Umum Daerah Dr. Mohamad Soewandhie, Jawa Timur, Indonesia

DOI:

https://doi.org/10.58344/jws.v2i9.425

Keywords:

mucinous tubular, spindle cell carcinoma, renal, computed tomography, magnetic resonance imaging, radical nephrectomy

Abstract

The objective of this research is to enhance the understanding and recognition of Mucinous Tubular and Spindle Cell Carcinoma of the Kidney (MTSCC-K), a rare renal tumor occurring in less than 1% of all renal tumors. The focus is on improving clinical diagnosis, understanding the tumor's characteristics, and exploring the prognosis and implications for patients. The method used in this research is a case study. The results of this research indicate that Clinical Presentation: MTSCC-K predominantly occurs in women and often presents with flank pain, similar to other renal tumors. However, it may lack other typical symptoms such as significant weight loss or urinary problems. Imaging Characteristics: CT scans may reveal solid masses with patchy calcification, often protruding outside the renal contour. These specific imaging features can aid in the differential diagnosis of MTSCC-K Histopathological Features: MTSCC-K is characterized by small, elongated cords or tubules arranged densely, with interspersed myxoid stroma. The presence of slender tubular spindle cell-like structures is a distinctive feature Prognosis: Patients with MTSCC-K, especially when diagnosed early and treated with radical nephrectomy, have a comparatively good prognosis compared to other renal cell carcinomas. The lack of identified metastases in the presented case also supports a positive prognosis. Implications of this research include: Increased awareness among doctors and radiologists about the unique clinical and imaging features of MTSCC-K can lead to faster and more accurate diagnoses.

References

Alves, A. S., Gaivão, A. M., Marques, R. C., & Matos, C. (2021). Two rare entities in one patient: mucinous tubular and spindle cell carcinoma of the kidney and peritoneal adenomyomas. Radiology Case Reports, 16(8), 1974–1979.

Bajpai, M., Pooja, S., Tyagi, M., & Pathre, A. (2022). Mucinous spindle and tubular renal cell cancer: A rare variant of renal cell cancer. Journal of Cancer Research and Therapeutics, 18(4), 1168–1170.

Ferro, T. J. dos S. F. (2013). Isolation, characterization and Ex-Vivo expansion of human synovial tissue derived-mesenchymal stem/stromal cells.

Gong, P., Zhuang, Q., Wang, X., Xu, R., Ding, T., Yin, S., & He, X. (2020). Mucinous tubular and spindle cell carcinoma of the kidney: Five case reports and review of the literature. Oncology Letters, 20(6), 1.

Kato, M., Soga, N., Arima, K., & Sugimura, Y. (2009). A case of renal mucinous tubular and spindle cell carcinoma. International Journal of Urology, 16(8), 699–701.

Kenney, P. A., Vikram, R., Prasad, S. R., Tamboli, P., Matin, S. F., Wood, C. G., & Karam, J. A. (2015). Mucinous tubular and spindle cell carcinoma (MTSCC) of the kidney: a detailed study of radiological, pathological and clinical outcomes. BJU International, 116(1), 85–92.

Moch, H., Cubilla, A. L., Humphrey, P. A., Reuter, V. E., & Ulbright, T. M. (2016). The 2016 WHO classification of tumours of the urinary system and male genital organs—part A: renal, penile, and testicular tumours. European Urology, 70(1), 93–105.

Mouracade, P., Kara, O., Maurice, M. J., Dagenais, J., Malkoc, E., Nelson, R. J., & Kaouk, J. H. (2017). Patterns and predictors of recurrence after partial nephrectomy for kidney tumors. The Journal of Urology, 197(6), 1403–1409.

Nathany, S., & Monappa, V. (2020). Mucinous tubular and spindle cell carcinoma: A review of histopathology and clinical and prognostic implications. Archives of Pathology & Laboratory Medicine, 144(1), 115–118.

Ozturk, H. (2015). 18F-fluorodeoxyglucose-positron-emission tomography/computed tomography staging of mucinous tubular and spindle cell carcinoma of the kidney. Indian Journal of Nuclear Medicine: IJNM: The Official Journal of the Society of Nuclear Medicine, India, 30(1), 68.

Ramya, N., Kanchan, M., Anand, R., & Shirley, S. (2022). A Case Report: Mucinous Tubular and Spindle Cell Carcinoma of Kidney with Spindle Cell Predominance Mimicking Mesenchymal Tumour. Journal of Kidney Cancer and VHL, 9(4), 10.

Sun, N., Fu, Y., Wang, Y., Tian, T., An, W., & Yuan, T. (2014). Mucinous tubular and spindle cell carcinoma of the kidney: A case report and review of the literature. Oncology Letters, 7(3), 811–814. https://doi.org/10.3892/ol.2014.1783

Thway, K., du Parcq, J., Larkin, J. M. G., Fisher, C., & Livni, N. (2012). Metastatic renal mucinous tubular and spindle cell carcinoma. Atypical behavior of a rare, morphologically bland tumor. Annals of Diagnostic Pathology, 16(5), 407–410. https://doi.org/https://doi.org/10.1016/j.anndiagpath.2011.04.001

Ursani, N. A., Robertson, A. R., Schieman, S. M., Bainbridge, T., & Srigley, J. R. (2011). Mucinous tubular and spindle cell carcinoma of kidney without sarcomatoid change showing metastases to liver and retroperitoneal lymph node. Human Pathology, 42(3), 444–448.

Wu, X., Chen, Y., Sha, J., Zhao, L., Huang, J., Bo, J., Liu, D., & Huang, Y. (2013). Renal mucinous tubular and spindle cell carcinoma: a report of 8 cases and review of the literature. Diagnostic Pathology, 8(1), 1–5.

Downloads

Published

2023-10-30

How to Cite

Pranesdha Putra, A. G., & Indrawan, T. . (2023). Mucinous Tubular and Spindle Cell Carcinoma of Kidney: A Case Report of a Rare Tumor. Journal of World Science, 2(9), 1454–1458. https://doi.org/10.58344/jws.v2i9.425