Stem Cell Therapy for Men’s Vitality in Supporting National Health and Defense: A Comprehensive Review and Meta-Analysis

Authors

  • Deby Susanti Pada Vinski Celltech Stem Cell Centre
  • Svetlana Trofimova Institute of Bioregulation and Gerontology St. Petersburg
  • Prihati Pujowaskito Universitas Pertahanan Indonesia
  • Markus Wibowo Rumah Sakit Pusat Pertahanan Negara (RSPPN) Panglima Besar Soedirman
  • Natasha Cinta Vinski Celltech Stem Cell Centre

DOI:

https://doi.org/10.58344/jws.v4i3.1317

Keywords:

men’s vitality, national health and defense, stem cell therapy

Abstract

This comprehensive review and meta-analysis examines the efficacy of stem cell therapy in enhancing men’s vitality while supporting national health and defense systems. Patient care records served as the primary source of data for evaluation and analysis, ensuring that real-world clinical outcomes were robustly captured. The study also evaluated the quality assurance of stem cell products cultured by the integrated Celltech Stem Cell Centre Laboratory and Banking, affirming that these products meet stringent clinical standards. Findings indicate that stem cell therapy possesses significant regenerative potential, particularly in repairing damaged cells. Notably, several patients who underwent therapy at the Celltech Stem Cell Center experienced remarkable functional recovery. These results underscore the therapeutic promise of stem cells not only for individual patient recovery but also as a strategic component in enhancing overall public health and national defense readiness.

References

Charitos, I. A., Ballini, A., Cantore, S., Boccellino, M., Di Domenico, M., Borsani, E., Nocini, R., Di Cosola, M., Santacroce, L., & Bottalico, L. (2021). Stem Cells: A Historical Review about Biological, Religious, and Ethical Issues. Stem Cells International, 2021. https://doi.org/10.1155/2021/9978837

Fang, J. Q. (2021). Statistical methods for biomedical research. World Scientific.

Harris, A. R., Walker, M. J., & Gilbert, F. (2022). Ethical and regulatory issues of stem cell-derived 3-dimensional organoid and tissue therapy for personalised regenerative medicine. BMC Medicine, 20(1). https://doi.org/10.1186/s12916-022-02710-9

Henschke, A. (2021). Ethics and National Security: A Case for Reasons in Decision-Making. In The Palgrave Handbook of National Security. Palgrave. https://doi.org/10.1007/978-3-030-53494-3_4

Hoang, T., Suh, J., & Sabharwal, M. (2022). Beyond a Numbers Game? Impact of Diversity and Inclusion on the Perception of Organizational Justice. Public Administration Review, 82(3). https://doi.org/10.1111/puar.13463

Ismail, H. Y., Hussein, S., Shaker, N. A., Rizk, H., & Wally, Y. R. (2023). Stem Cell Treatment Trials for Regeneration of Testicular Tissue in Laboratory Animals. Reproductive Sciences, 30(6). https://doi.org/10.1007/s43032-022-01152-1

Lee, J., Henderson, K., Massidda, M. W., Armenta-Ochoa, M., Im, B. G., Veith, A., Lee, B. K., Kim, M., Maceda, P., Yoon, E., Samarneh, L., Wong, M., Dunn, A. K., Kim, J., & Baker, A. B. (2021). Mechanobiological conditioning of mesenchymal stem cells for enhanced vascular regeneration. Nature Biomedical Engineering, 5(1). https://doi.org/10.1038/s41551-020-00674-w

Li, L., & Papadopoulos, V. (2021). Advances in stem cell research for the treatment of primary hypogonadism. Nature Reviews Urology, 18(8). https://doi.org/10.1038/s41585-021-00480-2

Miyagawa, S., Kainuma, S., Kawamura, T., Suzuki, K., Ito, Y., Iseoka, H., Ito, E., Takeda, M., Sasai, M., Mochizuki-Oda, N., Shimamoto, T., Nitta, Y., Dohi, H., Watabe, T., Sakata, Y., Toda, K., & Sawa, Y. (2022). Case report: Transplantation of human induced pluripotent stem cell-derived cardiomyocyte patches for ischemic cardiomyopathy. Frontiers in Cardiovascular Medicine, 9. https://doi.org/10.3389/fcvm.2022.950829

Nazari, H., Alborzi, F., Heirani-Tabasi, A., Hadizadeh, A., Asbagh, R. A., Behboudi, B., Fazeli, M. S., Rahimi, M., Keramati, M. R., Keshvari, A., Kazemeini, A., Soleimani, M., & Ahmadi Tafti, S. M. (2022). Evaluating the safety and efficacy of mesenchymal stem cell-derived exosomes for treatment of refractory perianal fistula in IBD patients: Clinical trial phase i. Gastroenterology Report, 10. https://doi.org/10.1093/gastro/goac075

Phogat, R., Manjunath, B. C., Sabbarwal, B., Bhatnagar, A., Reena, & Anand, D. (2023). Misconduct in biomedical research: A meta-analysis and systematic review. Journal of International Society of Preventive and Community Dentistry, 13(3). https://doi.org/10.4103/jispcd.jispcd_220_22

Sangiorgi, G., Cereda, A., Benedetto, D., Bonanni, M., Chiricolo, G., Cota, L., Martuscelli, E., & Greco, F. (2021). Anatomy, pathophysiology, molecular mechanisms, and clinical management of erectile dysfunction in patients affected by coronary artery disease: A review. Biomedicines, 9(4). https://doi.org/10.3390/biomedicines9040432

Scala, P., Rehak, L., Giudice, V., Ciaglia, E., Puca, A. A., Selleri, C., Porta, G. Della, & Maffulli, N. (2021). Stem cell and macrophage roles in skeletal muscle regenerative medicine. International Journal of Molecular Sciences, 22(19). https://doi.org/10.3390/ijms221910867

Shang, F., Yu, Y., Liu, S., Ming, L., Zhang, Y., Zhou, Z., Zhao, J., & Jin, Y. (2021). Advancing application of mesenchymal stem cell-based bone tissue regeneration. Bioactive Materials, 6(3). https://doi.org/10.1016/j.bioactmat.2020.08.014

Taherdoost, H. (2022). What are Different Research Approaches? Comprehensive Review of Qualitative, Quantitative, and Mixed Method Research, Their Applications, Types, and Limitations. Journal of Management Science & Engineering Research, 5(1). https://doi.org/10.30564/jmser.v5i1.4538

Thanh, L. N., Dam, P. T. M., Nguyen, H. P., Nguyen, T. S. T., To, H. M., Nguyen, H. B., Luu, N. A., & Hoang, D. M. (2021). Can Autologous Adipose-Derived Mesenchymal Stem Cell Transplantation Improve Sexual Function in People with Sexual Functional Deficiency? Stem Cell Reviews and Reports, 17(6). https://doi.org/10.1007/s12015-021-10196-w

Wu, J. X., Xia, T., She, L. P., Lin, S., & Luo, X. M. (2022). Stem Cell Therapies for Human Infertility: Advantages and Challenges. Cell Transplantation, 31. https://doi.org/10.1177/09636897221083252

Xu, X., Xu, L., Xia, J., Wen, C., Liang, Y., & Zhang, Y. (2023). Harnessing knee joint resident mesenchymal stem cells in cartilage tissue engineering. Acta Biomaterialia, 168. https://doi.org/10.1016/j.actbio.2023.07.024

Yang, Y., Lee, E. H., & Yang, Z. (2022). Hypoxia-Conditioned Mesenchymal Stem Cells in Tissue Regeneration Application. Tissue Engineering - Part B: Reviews, 28(5). https://doi.org/10.1089/ten.teb.2021.0145

Zang, L., Li, Y., Hao, H., Liu, J., Cheng, Y., Li, B., Yin, Y., Zhang, Q., Gao, F., Wang, H., Gu, S., Li, J., Lin, F., Zhu, Y., Tian, G., Chen, Y., Gu, W., Du, J., Chen, K., … Mu, Y. (2022). Efficacy and safety of umbilical cord-derived mesenchymal stem cells in Chinese adults with type 2 diabetes: a single-center, double-blinded, randomized, placebo-controlled phase II trial. Stem Cell Research and Therapy, 13(1). https://doi.org/10.1186/s13287-022-02848-6

Downloads

Published

2025-03-20

How to Cite

Vinski, D. S. P., Trofimova, S., Pujowaskito, P., Wibowo, M., & Vinski, N. C. (2025). Stem Cell Therapy for Men’s Vitality in Supporting National Health and Defense: A Comprehensive Review and Meta-Analysis. Journal of World Science, 4(3), 307–316. https://doi.org/10.58344/jws.v4i3.1317

Most read articles by the same author(s)